Vascular effects of procaine amide in the dog. Predominance of the inhibitory effect on ganglionic transmission.

نویسندگان

  • P G Schmid
  • L D Nelson
  • D D Heistad
  • A L Mark
  • F M Abboud
چکیده

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Vascular Effects of Procaine Amide in the Dog

The mechanism of the vasodilator effect of procaine amide in dogs was investigated in isolated gracilis muscle and hindpaw perfused at constant flows with arterial blood. Inhibition of sympathetic ganglionic transmission contributed predominantly to the vasodilatation in muscle that accompanied intravenous administration of procaine amide (20 mg/kg). In contrast, comparable amounts of procaine ...

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عنوان ژورنال:
  • Circulation research

دوره 35 6  شماره 

صفحات  -

تاریخ انتشار 1974